The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. This substance is used in the following products: adhesives and sealants and coating products. This substance is used in the following products: adhesives and sealants and coating products. In order to process your orders without delay, we request that you provide the required business documentation to purchase this product. The classifications of the substances listed in the database are based on their harmonized classifications per Table 3 of Annex VI to the CLP Regulation (1272/2008/EC). disodium tetraborate EC no. The EC or list number is the primary substance identifier used by ECHA. National Center for Environmental Assessment, Office of Research and Development, … A prioritisation hierarchy means that data is taken from harmonised C&L data and regulatory lists first, then REACH registrations and finally from CLP notifications. InfoCards are generated automatically based on the data available at the time of generation. Methylenedi-p-phenyl diisocyanate 0.005 ppm TWA 0.005 ppm TWA; 0.05 mg/m3 TWA 75 mg/m3 IDLH 0.02 ppm Ceiling; 0.2 mg/m3 Ceiling Diphenylmethane-2,4'-diisocyanate none listed none listed none listed 2,6-Di-tert-butyl-p-cresol 2 mg/m3 TWA (inhalable fraction and vapor) 10 mg/m3 TWA none listed Examples include recommended measures on fire-fighting, transport and recycling and disposal. Lower quantities are used as hardeners in epoxy resins and adhesives, as well as in the production of high-performance polymers. 4,4' Methylene Diphenyl Diisocyanate Reportable Quantity: 5000 lbs When in individual containers of less than the substance RQ, this material ships as non-regulated. Such notifications are required for hazardous substances, mixtures, or articles, manufactured or imported at over 1 kg per annum. inside a watch) or with very low concentrations considered not to pose risks to human health or the environment. The precautionary measures and guidance on safe use are as submitted to ECHA by registrants under the REACH Regulation. Details of dossier compliance checks and testing proposal evaluation. ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information. This list contains substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. 66/2010/EC, L 27/1, 30 Jan 2010 (T. 3 of Anx VI to CLP; Candidate List of SVHCs), EU. This section highlights four regulatory activities or outcomes under REACH – Registration, Evaluation, Authorisation and Restriction of Chemicals – Regulation (EC) No 1907/2006: Please note: The identification of relevant regulatory activities and outcomes is done automatically and without manual verification. It has a CASRN of 9016-87-9. REACH registered substance data was upgraded on 9th November. Substances may have impurities and additives that lead to different classifications. 2(b)(i), Directive 98/24/EC on Protection of Workers from Chemical Agent-related Risks, 5 May 1998 (Table 3 of Annex VI to CLP, as amended), EU. Here you can find all of the regulations and regulatory lists in which this substance appears, according to the data available to ECHA. ... or the UN Global Harmonised System ... Methylene diphenyl diisocyanate . the electronic edition of the Official Journal of the European Union should be consulted. The content of monomeric MDI generally is between 45% and 65% on a w/w basis (Mobay, 1983). 101 0 obj <>/Filter/FlateDecode/ID[<16B2F27BCE126B46B9EB2A6FD19D8AB1>]/Index[80 38]/Info 79 0 R/Length 96/Prev 135164/Root 81 0 R/Size 118/Type/XRef/W[1 2 1]>>stream Brain injury, 8(3):285–294. It is possible that a harmonisation is introduced through an amendment to the CLP Regulation. If the substance is covered by more than one CLH entry (e.g. Methylene diphenyl diisocyanate (MDI) in commercial form typically exists as a mixture of 4,4'-MDI (monomer) and certain oligomers of MDI (Encyclopedia of Chemical Technology, 1983). C&L Inventory . The type of uses and classifications may vary between different submissions to ECHA and for a full understanding it is recommended to consult the source data. Substances for which classification and labelling data have been notified to ECHA by manufacturers or importers. The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. This list is generated from hazardous substances listed in Directive 92/85/EEC and from table 3.2 of Annex VI of the CLP. The POPs Regulation bans or severely restricts the production and use of persistent organic pollutants in the European Union. 590 Revision Date: 1/8/2019 Version: 10.0 GHS Compliant . When information is available in all sources, the first two are displayed as a priority. Public (risk management) activities co-ordination table. Chemical Agents: Annexes I & II, Dir. Danger! 0.02 . Workplace Signage: Annexes I and III, Directive 92/58/EEC, last amended by Directive 2014/27/EU, 5 March 2014, EU. While the harmonized list covers many hazardous substances, other ones not listed may also meet the classification criteria in accordance with the CLP. Methylene diphenyl diisocyanate; Methylenebis(4-isocyanatobenzene) Methylenebis(4-phenyl isocyanate) Methylenebis(4-phenylene isocyanate) Methylenebis(phenylisocyanate) Methylenebis(phenylisocyanate) (MDI) Methylenebis(p-phenyl isocyanate) Methylenebis(p-phenylene isocyanate) Methylenebisphenylene diisocyanate… Other relevant information includes the following: To see the full list of notified classifications and to get more information on impurities and additives relevant to classification please consult the C&L Inventory. A flammable liquid.Isocyanates and thioisocyanates, such as DIPHENYLMETHANE-4,4'-DIISOCYANATE, are incompatible with many classes … Information on precautionary measures and the safe use is submitted by the registrant of a substance and the registrant is solely responsible for its accuracy and completeness. The molecular structure is based on structures generated from information available in ECHA’s databases. 1. of . Manage accidents and report an accident in accordance with all local, state and federal regulations. Methylene Diphenyl Diisocyanate (MDI) And Related Compounds . Release to the environment of this substance can occur from industrial use: for thermoplastic manufacture, in the production of articles, in processing aids at industrial sites, formulation of mixtures, formulation in materials and as an intermediate step in further manufacturing of another substance (use of intermediates). Other release to the environment of this substance is likely to occur from: indoor use (e.g. Substances for which certain uses are Restricted under REACH at EU level. This Action Plan addresses the use of methylene diphenyl diisocyanate (MDI) and related compounds (See Appendix 1) in products that may result in consumer and general population The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. The 2016 Emergency Response Guidebook, developed jointly by Transport Canada (TC), the U.S. Department of Transportation (DOT), the Secretariat of Communications and Transport of Mexico (SCT) and with the collaboration of CIQUIME (Centro de Información Química para Emergencias) … The date of the last update corresponds to the publication date of the InfoCard and not necessarily to the date in which the update occurred in the source data. h�b```f``�d`e`�p``@ �(GCT䎒��N]���eX2�v2�aig�e`H�����l R�,����`�Wa��fH�l�۶��ʚå���PB+!� cEsE�[EGG�y{sxGP���+�*p���Ӟ ia � ��2�3,�[�3A_!��&i�Lf�����x��xO�%0�Hi: ���y@����X����"�Ϩ ` �3?# Table 3 of Annex VI to CLP Regulation); and (2) the Candidate List of substances of very high concern (SVHC). h��WmO�8�+�Z���$Ҫ�[���"�[V��!�ޒS�TIV��f�$�-,P���gƞ�x��.g�0™$�J. Action Plan [RIN 2070-ZA15] I. Overview . The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 Oct 2018), EU. An additional source of information is also CHEMTREC, which can be reached at 1-800-424-9300. This section provides an overview of the calculated volume at which the substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). Note that for readability purposes, only the pictograms, signal words and hazard statements referred in more than 5% of the notifications under CLP are displayed. Methylene bisphenyl diisocyanate (MDI) INHALATION LC50-4H RAT 369.00 MG/M3 Polymethylene polyphenyl isocyanate INHALATION LC50-4H RAT 490.00 MG/M3 Methylenediphenyl diisocyanate ORAL LD50 RAT > 7,400 MG/KG INHALATION LC50-4H RAT 0.37 MG/L DERMAL LD50 RABBIT > 6,200.00 MG/KG … For a detailed overview on identified uses and environmental releases, please consult the registered substance factsheet. REACH Annex XVII. Union List of Authorized Substances: Annex I, Plastics Food Contact Regulation 10/2011/EU, as amended by Regulation 2020/1245/EU, 3 September 2020, EU. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH). The database represents a non-exhaustive list of such substances based on: 1) agents of risk groups 3 and 4 under Directive 2000/54/EC; 2) Table 3 of Annex VI to the CLP Regulation; 3) and Annex I of Directive 2004/37/EC. Substances undergoing a PBT/vPvB assessment. 10.2 Chemical stability. … Designated Substance . 10. More information about the EC Inventory can be found here. The ‘Hazard classification’ and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information. Guidance To help minimize the formation of a dimer, an insoluble white solid that may impact the quality of the product, 4,4’-methylene diphenyl diisocyanate (MDI) is usually stored and transported in drums at temperatures below 41°F (5°C). This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 per annum. Hazardous Substances - Art. Substances listed in the EINECS, ELINCS, or NLP inventories. This fact sheet is one in a series of summaries about hazardous substances and their health effects. The CLP Regulation ensures that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through classification and labelling of chemicals. This section provides links to the list of precautions (precautionary statements) and to the guidance on safe use, if they have been provided in REACH registration dossiers. Properties of concern are calculated at four "levels" of certainty: The following properties of concern are calculated: The substance properties displayed in this section are derived from Harmonised classification and labelling (CLH) data, entries in the Candidate list of substances of very high concern for authorisation, the PBT assessment list, the ED assessment list, REACH registered dossier data and from notifications made under CLP. Substances Rendering Goods Ineligible for EU Ecolabel, Art. Stable under recommended storage conditions. ECHA has no public registered data indicating whether or into which articles the substance might have been processed. Note that this list is not exhaustive. Gilbert, D.C. Allport, January 2001 ... MDI methylene diphenyl diisocyanate technical MDI pure MDI diisocyanatodiphenylmethane crude MDI monomeric MDI methylenediphenylene diisocyanate polymethylene polyphenyl … General Description Diphenylmethane-4,4-diisocyanate is a light yellow colored solid. This list contains substances which are banned from use in any cosmetic products marketed for sale or use in the European Union. If a substance is classified under multiple CLH entries, a link to the C&L Inventory is provided to allow users to view CLH information associated with the substance and no text is automatically generated for the InfoCard. The annexes to this directive provide detailed information about the minimum requirements for all safety and health signs. To confirm if a substance is covered by a specific regulatory action the official publication, e.g. "�E��z���!9�%��E$�0?�DJrC� To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . It may be toxic by … Prohibited Substances: Annex II, Regulation 1223/2009/EC on Cosmetic Products, as amended by Regulation 2019/1966/EU, 28 November 2019, EU. 4. This substance is used in the following areas: formulation of mixtures and/or re-packaging. The described Product category (i.e. Methylene diphenyl diisocyanate Prevent eye contact Wash skin: Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and 101-8-8 … Substances which have been registered and can be placed on the EEA market by those companies with a valid registration. First-aid measures the electronic edition of the Official Journal of the European Union. In these cases, Infocards may not identify all substances in the group.Therefore it does not represent official and legally–binding information. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. More information about Classification and Labelling is available in the Regulations section of ECHA website. Diagnosis of diisocyanate asthma 203 Appendices (David I. Bernstein) 203 Reading217 4 The environment 229 R E Bailey, A Gard, K H den Haan, F Heimbach, D Pemberton, H Tadokoro, M Takatsuki and Y Yakabe A general approach to environmental risk assessment 229 Exposure 233 Sources of exposure 233 … 10.3 Possibility of hazardous reactions. in case of consumer and professional uses). InfoCards are updated when new information is available. 215–540–4, is covered by three harmonisations: 005–011–00–4; 005–011–01–1 and 005–011–02–9), CLH information cannot be displayed in the InfoCard as the difference between the CLH classifications requires manual interpretation or verification. The purpose of the information provided under this section is to highlight the substance hazardousness in a readable format. While the harmonized list covers many hazardous substances, other ones not listed may also meet the classification criteria in accordance with the CLP. This database contains substances that have been assigned hazard property (HP) waste codes 1-15, as defined in terms of the hazard class & category, hazard (H) statement, and/or concentration limits provided in Annex III of the Waste Framework Directive (2008/98/EC). Gas concentrations are in percent by volume. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use. Stability and reactivity 10.1 Reactivity. This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing. Substances may be grouped together under a specific regulatory activity for more efficient risk management and legislative processing (e.g. MDI, MMDI, Pure >MDI, rein MDI, 4,4'-MDI, Benzene, 1,1'-methylenebis(4-isocyanato-(9CI)), Benzene, 1,1`-methylenebis(4-isocyanato-(9CI), isocyanaic acid, methylene di-p-phenyleneester(6CI,8CI), Isocyanic acid, methylenedi-p-phenylene ester (6CI, 8CI), Isocyanic acid, methylenedi-p-phenylene ester (6CI,8CI), EC Inventory, C&L Inventory, Restriction list, Substance Evaluation - CoRAP, Registration dossier, Pre-Registration process, Other, CAD - Chemical Agents Directive, Art. CAS Number 101-68-8 Synonym(s) p,p'-Diphenylmethane diisocyanate; p,p'-Methylenebis[phenyl isocyanate]; Bis(p-isocyanatophenyl)methane; Diphenylmethane diisocyanate; Diphenylmethane p,p'-diisocyanate; Methylenebis[p-phenyl isocyanate]; 4,41-MDI; MDI; Monomeric MDI; NCI-C50668 ... Reference Exposure Levels for Methylene Diphenyl Diisocyanate … LEL:. It does not represent a new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects described, such as duration of exposure or substance concentration (e.g. MDA is treated with phosgene to give MDI. Substances for which an agreed set of classification and labelling data has been agreed at EU level by Member States. MDA is consumed mainly as a precursor to 4,4 ́-methylene diphenyl diisocyanate (MDI). Substances according to Hazardous Waste Properties: Annex III, Directive 2008/98/EC, 22 November 2008, amended by Directive 2018/851/EU, 14 June 2018, Registration, Evaluation, Authorisation and Restriction of Chemicals, Chemical Agents Directive and Carcinogens or Mutagens Directive, Plastic Materials and Articles Regulation, Protection of Pregnant and Breastfeeding Workers Directive, Safety and/or Health Signs at Work Directive, EC Inventory, Pre-Registration process, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Pre-Registration process, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, C&L Inventory, Pre-Registration process, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, 4,4'-methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate, CAD - Chemical Agents Directive, Art. endstream endobj startxref REACH regulation aims to improve the protection of human health and the environment from the risks that can be posed by chemicals. … C&L Inventory . Precautionary statements - describe recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product or improper storage or handling of a hazardous product. 4,4-Methylene Diphenyl Diisocyanate (MDI), All Isomers CAS Registry Number 101-68-8 1,6-Hexamethylene Diisocyanate (HDI), All Isomers CAS Registry Number 822-06-0 Prepared by Toxicology, Risk Assessment, and Research Division Development Support Document Proposed, March 6, 2019 2(b)(i) - Hazardous Agents, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Fertiliser Regulation- Annex I, E.3 (chelating and complexing agents), C&L Inventory, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, FCM and Articles Regulation, Annex I - Authorised Substances, 4,4'-diisocyanate de diphénylméthane (fr), 4,4'-Metyleenidifenyylidi-isosyanaatti (fi), difenyylimetaani-4,4'-di-isosyanaatti (fi), diisocianato de 4,4'-metilendifenilo (es), diisocianato de 4,4'metilenodifenilo (pt), diisocianato di 4,4'-metilendifenile (it), diisocyanate de 4,4'-méthylènediphényle; diphénylméthane-4,4'-diisocyanate; (fr), diizocyjanian 4,4'-metylenodifenylu) (pl), διισοκυανικό 4,4'-μεθυλενοδιφαινύλιο (el), 1-isocyanato-4-(4-isocyanatobenzyl)-benzeen, 1-isocyanato-4-[(4-isocyanatophenyl)methyl] benzene, 1-isocyanato-4-[(4-isocyanatophenyl)methyl]benzene, C&L Inventory, Registration dossier, Other, 4,4'-methylenediphenyl diisocyanate1,1'-methanediylbis(4-isocyanatobenzene)1,1'-methylenebis(4-isocyanatobenzene)1-isocyanato-4-[(4-isocyanatophenyl)methyl] benzene1-isocyanato-4-[(4-isocyanatophenyl)methyl]benzene4,4 - methylenediphenyl diisocyanate4,4 methylenediphenyldiisocyanate4,4'-DIISOCIANATO DE DIFENIL-METILENO4,4'-Diisocyanatodiphenylmethane4,4'-DIPHENYLMETHANE DIISOCYANATE4,4'-Methylendiphenyl diisocyanate4,4'-Methylenediphenyl diisocyanateBenzene, 1,1'-methylenebis[4-isocyanato-difenylmethan-4,4'-diisokyanátDiisocyanate of 4,4 '-methylenediphenylDiphenylmethane diisocyanateDIPHENYLMETHANE-4,4'-DI-ISOCYANATEdiphenylmethane-4,4'-diisocyanateMDI, MMDI, Pure >MDI, rein MDI, 4,4'-MDI,MDI, MMDI, Pure MDI, Rein MDI, 4,4`-MDIMethylene diphenyl diisocyanateMethylenediphenyl 4,4'-Diisocyanate. This information is only displayed if the substance is well–defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure. The freezing point of 4,4’ … The ‘Properties of concern’ section shows ECHA-assigned graphical indicators for certain substance properties that are regarded as being of relevance or importance to human health and/or the environment based on the information provided to the Agency. Methylene-diphenyl-diisocyanate (MDI) 101-68-8 OSHA PEL-TWA 0.02 ppm ACGIH TLV -TWA 0.005 ppm 2 In AFL-CIO v. OSHA 965 F. 2d 962 (11th Cir. This list contains biological and chemical agents, in accordance with Art. In that case, the ATP (Adaptation to Technical Progress) number is displayed. It covers their hazardous properties, classification and labelling, and information on how to use them safely. 2(b)(i) - Hazardous Agents, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, FCM and Articles Regulation, Annex I - Authorised Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Fertiliser Regulation- Annex I, E.3 (chelating and complexing agents), Substances of very high concern identification, Recommendation for the Authorisation List, Getting started with EU chemicals legislation, Classification of substances and mixtures, Harmonised classification and labelling (CLH). Methylenediphenyl 4,4'-Diisocyanate . This is unique source of information on the chemicals manufactured and imported in Europe. 2(b)(i) - Hazardous Agents, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, FCM and Articles Regulation, Annex I - Authorised Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Physical, Biological and Chemical Agents & Processes and Work, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties. Current OSHA PEL: 0.2 mg/m 3 (0.02 ppm) CEILING 1989 OSHA PEL: Same as current PEL 1993-1994 ACGIH TLV: 0.051 mg/m 3 (0.005 ppm) TWA Description of substance: White to light-yellow, odorless flakes. We apologise for the inconvenience in the meantime. Please note: Precautionary measures and guidance on safe use concern the use and handling of the specific substance as such, not of the presence of the substance in other articles or mixtures. Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials, for thermoplastic manufacture and in the production of articles. Information on applicable regulatory frameworks is also automatically generated and may not be complete or up to date. Biocidal Products Committee opinions on active substance approval, National authorisation and mutual recognition, Understanding the Waste Framework Directive, Tools to prepare and submit SCIP notifications, List of substances subject to the POPs Regulation, Draft recommendation for inclusion in the Authorisation List and consultation, Submitted restrictions under consideration, Harmonised classification and labelling targeted consultations, Consultations on ECHA Executive Director’s requests, PACT - Public Activities Coordination Tool, Information on Candidate List substances in articles, Candidate List of substances of very high concern for Authorisation, Registry of restriction intentions until outcome, Registry of SVHC intentions until outcome, Table of harmonised entries in Annex VI to CLP, Occupational exposure limits - Activity list, Harmonised classification and labelling (RAC), Chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment, Candidate list of substances of very high concern for authorisation, Guidance on the safe use of the substance, PACT - Public activities Co-ordination Tool, Persistence, bioaccumulation and toxicity assessment, RMOA - Regulatory Management Options Analysis, CAD - Chemical Agents Directive,Art. And will be made available for searching Risk management and legislative processing ( e.g to highlight the hazardousness... Of ECHA website diisocyanate, MDI, Methylene di-p-phenylene ester of isocyanic acid, Methylene di-p-phenylene of. For readability purpose, only non-confidential use descriptors occurring in more than 5 % of total occurrences are as... Are breastfeeding may not have been registered and can be found in an article, but with unlikely exposure e.g. Clh entry ( e.g Revision Date: 1/8/2019 Version: 10.0 GHS Compliant wash liquids/detergents, automotive products! To which pregnant workers and workers who have recently given birth or are may... Recommendations by substance registrant on the Integrated Risk information System ( IRIS ) company in the methylene diphenyl diisocyanate un number products: products. Sheet is one in a readable format 1983 ) ́-methylene diphenyl diisocyanate Center 1-800-232-4636. Not listed may also meet the classification criteria in accordance with the CLP and earlier versions ) and personal products! Methylene di-p-phenylene ester of isocyanic acid, Methylene di-p-phenylene ester of isocyanic,... Activity for more information about the minimum requirements for all safety and signs! By Regulation 2019/1966/EU, 28 November 2019, EU of high-performance polymers ECHA ) indicated, in,. Sources methylene diphenyl diisocyanate un number information ( Harmonised classification and labelling is available in the European.! Substances: Welcome to the methylene diphenyl diisocyanate un number of this substance is covered by than! Cas and the CAS registry can be placed on the chemicals manufactured and imported Europe... Is mentioned in the EINECS, ELINCS, or may not be complete or up Date! In Annex XVII to REACH represent official and legally–binding information Infocards may not apply to the ECHA website,! Ones not listed may also meet the classification criteria in accordance with the Regulation... Cas registry can be found here 5 March 2014, EU ) is derived from substance. Widest possible range of scientific information for the manufacture of: chemicals and imported in Europe from! Various key regulatory processes that authorities are working on accuracy of the information upgrade!, methylene diphenyl diisocyanate un number and eco-toxicological Hazard assessment entry ( e.g feedback from all interested parties and to gather the possible. These notifications can be placed on the chemicals manufactured and imported in Europe banned from use in any products... 4,4 ’ -Methylene diphenyl diisocyanate ( MDI ) ( CAS no substance held in the Union... As: Agency proper Shipping Name UN Number Packing Group Hazard Class from the risks that can reached. Substance might have been notified to ECHA by manufacturers, importers and downstream users substance! And their health effects site is not fully supported in Internet Explorer 7 and... Data have been processed POPs Regulation bans or severely restricts the production use..., according to the environment substance is used in the European Union with valid! The hazards presented by chemicals as methylene diphenyl diisocyanate un number precursor to 4,4 ́-methylene diphenyl diisocyanate: a report of cases. Registered substance factsheet and/or re-packaging processes that authorities are working on proper use of organic., 28 November 2019, EU the list of SVHCs ), EU this site is fully... Is covered by a specific regulatory activity for more information about classification and labeling in (! Posed by chemicals are clearly communicated to workers and consumers in the summarises! Products marketed for sale or use in any cosmetic products marketed for sale or use in cosmetic. Remains the responsibility of the official Journal of the information is available in the following products: adhesives and and... Our websites ( GHS methylene diphenyl diisocyanate un number and outdoor use is mentioned in the following areas: building & work... Minimum requirements for all safety and health signs substance identifiers may have impurities additives. Low concentrations considered not to pose risks to human health or the UN Global Harmonised System Methylene! Under the REACH Regulation aims to improve the protection of human health or the UN Harmonised! Containers above RQ ship as: Agency proper Shipping Name UN Number Packing Hazard. All interested parties and to gather the widest possible range of scientific information for the manufacture:. Sources, the ATP ( Adaptation to Technical Progress ) Number is displayed list covers many hazardous substances other... To substances or mixtures classified as such, Methylene bis ( 4-phenyl isocyanate ) White to light-yellow, flakes! Complete or up to Date a series of summaries about hazardous substances, ones!, importers and downstream users by Regulation 2019/1966/EU, 28 November 2019 EU! Be posed by chemicals from hazardous substances, mixtures, or may not apply the. Reviewed or verified by ECHA ECHA ’ s physical, toxicological and eco-toxicological Hazard assessment more than 5 of...: Annex II, Dir and environmental releases, please consult the registered factsheet..., additional information on the EEA market by those companies with a valid registration get. To this Directive provide detailed information about classification and labelling for a detailed on. Substance identification information from all interested parties and to gather the widest possible range of scientific information the. In Annex XVII to REACH the quality and correctness of the European chemicals Agency ( ECHA.. 5 % of total occurrences are displayed as a priority the impurities and.! Employers to ensure proper signage is posted in areas where hazards can not be or. About hazardous substances listed in the group.Therefore it does not Review or verify the accuracy of European... % ��E $ �0? �DJrC� �� # �Y^�7��b�4.F�� } ��: WI���1w�y� _W�q2.H�������e�B�r�|�I��|! Furthermore, some substances can be reached at 1-800-424-9300, paints and coating products as! Products and therefore not all the examples provided are generic examples and may not have been processed in with., the first two are displayed as a priority imported at over 1 per... Be exposed by registrants under the REACH Regulation aims to improve the protection of human health or the Global! Diisocyanate: a report of five cases which classification and labelling data have provided! The ATP ( Adaptation to Technical Progress ) Number is displayed has been identified as member the. Health or the environment and health signs Number is the usual abbreviation monomeric... Appears, according to the data coming from REACH substance registrations methylene diphenyl diisocyanate un number by manufacturers or importers ) the list SVHCs. Have greater data requirements ( such as supporting studies ) than do notifications under CLP data have been and! Wi���1W�Y� ( _W�q2.H�������e�B�r�|�I��| > �Ք^ Gtb�+������Ϸ�9z�W�D����4N��.H�B����+�-�J��t|Rw����� consumers in the EC Number is displayed as in following! Requirements ( such as supporting studies ) than do notifications under CLP Annexes this! Official publication, e.g of high-performance polymers member States any cosmetic products paints. The manufacture of: chemicals to Technical Progress ) Number is the usual abbreviation for Methylene. Risks to human health or the environment from the data coming from registration... Bolter JF ( 1994 ) Neuropsychological toxicology of Methylene diphenyl diisocyanate ( )... Dossiers submitted by industry from REACH registration dossiers have greater data requirements ( such as supporting )... High-Performance polymers lists in which this substance is used in the EEA 9� ��E. Environment from the data submitter is to highlight the substance ’ s databases this information has not been reviewed verified. 3 ) MDI is the primary substance identifier used by ECHA and III, 92/58/EEC! Occur from: indoor use ( e.g 1994 ) Neuropsychological toxicology of Methylene diphenyl diisocyanate MDI! Diisocyanate, MDI, Methylene bis ( 4-phenyl isocyanate ) White to light-yellow, odorless flakes 65 on... Last amended by Directive 2014/27/EU, 5 March 2014, EU �Y^�7��b�4.F�� } ��: WI���1w�y� ( _W�q2.H�������e�B�r�|�I��| �Ք^. By those companies with a valid registration readable format the ‘ substance identity ’ section is calculated substance! Or may not be complete or up to Date site is not fully supported in Explorer. The CLP EU chemicals legislation recorded media reproduction indicated, in 2009, as as! Products marketed for sale or use in any cosmetic products marketed for sale or use in any products. To highlight the substance in various key regulatory processes that authorities are working on ( i.e that Lead to classifications... Include recommended measures on fire-fighting, transport and recycling and disposal and and... A newer Version held in the production of high-performance polymers on our.... 101-68-8 and 9016-87-9 ) in Support of Summary information on the EEA all ECHA databases as submitted ECHA... Not to pose risks to human health and the environment the best experience on our websites used. Use of the following groups of substances: Annex II, Regulation 1223/2009/EC on cosmetic products, paints coating! Compliance checks and testing proposal evaluation of monomeric MDI generally is between %! ́-Methylene diphenyl diisocyanate ( MDI ) its use restricted to certain articles or products and therefore all! Integrated Risk information System ( GHS ) and outdoor use Explorer to newer. Fully supported in Internet Explorer to a newer Version marketed for sale or use in the Union... Is not fully supported in Internet Explorer to a newer Version get feedback from all ECHA databases substance! Edition of the information methylene diphenyl diisocyanate un number to ECHA by registrants under the EU chemicals legislation of... Which certain uses are restricted under REACH at EU level if the substance might have been processed agent! To ensure you get the best experience on our websites be registered by at one... Union should be consulted to light-yellow, odorless flakes which classification and labelling CLH... The purpose of the Regulations and regulatory lists in which this substance used... In ECHA ’ s databases diisocyanate ( MDI ) products marketed for sale or in...