Now what caffeine does is tell your body that your not tired. 0 comment. I can down two cups before bed and still sleep soundly, which I know shouldn't be the case. Caffeine is considered a drug which means it affects your mind. A 45-year-old member asked: Can there be an energy drink or something that doesn't rely on caffeine? Caffeine can disrupt sleep and reduce blood flow to the brain in most people. 1. I’ve never drank coffee or taken energy drinks, so I don’t understand why caffeine doesn’t affect my body. One is a 6 hour hand life, the other is a 3 hour half life. Dr. Yash Khanna answered. Also, there are two common liver enzymes in the population fur metabolism of caffeine. Why doesn't caffeine affect me? =) Caffeine is the most widely consumed stimulant in the world.That being said, it does not affect everyone in the same way. I am going to try a stimulant med soon, so far strattera doesn't seem to be enough anymore. Also Know, why does caffeine have the opposite effect on me? There is also a general belief that caffeine makes people more anxious and hinders sleep. To be sure, coffee is safe. Send thanks to the doctor. According to the U.S. Food and Drug Administration, the average American consumes 300 milligrams of caffeine each day, and the Mayo Clinic says it is safe for adults to consume upward of 400 milligrams daily-- the equivalent of four cups of coffee.It is our most popular caffeine delivery mechanism by magnitudes, and provides quite a few health benefits as well. Studying how genes affect coffee consumption habits is nothing new. 0. I swallowed two 200mg caffeine pills yesterday and then downed a 175 mg caffeine pre workout yet I still don’t feel energized or affected at all. In … So, I've never had a ton of caffeine to be able to build up a tolerance to it, but it still doesn't affect me in a way that wakes me up, it just helps relax my body. Many sufferers find it has the opposite effect than it does in other people: instead of making them more active and stimulated, it actually has more of a “calm-down” effect, and encourages sleep. Why caffeine doesn’t leave everybody wired. Thanks! However, it has a different effect on people with ADHD. In the following picture, you can see what happens when you’ve built up a caffeine tolerance: If you decide to increase your daily coffee consumption just know that according to the FDA you shouldn’t go over 400 mg of caffeine per day . Or is supposed to unless you tell your body it doesn't. Norepinephren: These substances increase the effect of norepinephren an excitatory brain chemical. If anyone can tell me why or why they think why I would appreciate it. Caffeine can also affect sensitive people's GI tract, causing some rather unpleasant side effects. Call me crazy but I love it and prefer it over any other drink. Learn what it does. 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